In vitro selection of murine B16 melanoma variants with enhanced tissue-invasive properties.

Enhanced Tissue-invasive Properties Selection of Murine B16 Melanoma Variants with In Vitro

New assay methods have been devised to quantitate tumor cell invasion of tissues of differing histological complexity main tained as organ cultures in vitro (chorioallantoic membrane of chicken, mouse urinary bladder, and canine blood vessel). In addition to quantitating tumor cell invasion, these methods also allow recovery of invasive cells for comparison with noninvasive cells. These methods...

Use of Mycobacterium vaccae (SRLI72) as an Immunomodulating Agent in Association with Murine Melanoma Model B16-F10

Evaluation of Antioxidant and Anti-Melanogenic Activity of Different Extracts of Aerial Parts of N. Sintenisii in Murine Melanoma B16F10 Cells

Nepeta (Lamiaceae) is an important genus with beneficial medicinal properties. N. sintenisiiBornm. has been used in folk medicine of Iran to cure various diseases. We investigated theanti-melanogenesis effects of n-hexane, MeOH, CH2Cl2, n-BuOH, EtOAc, and H2O extractsisolated from the plant in B16 melanoma cells. Various assays including cytotoxicity, mushroomtyrosinase inhibition, inhibition o...

Evaluation of antioxidant and anti-melanogenic activities of different extracts from aerial parts of Nepeta binaludensis Jamzad in murine melanoma B16F10 cells

Objective(s): Nepeta binaludensis Jamzad (Lamiaceae) has been used in folk medicine of Iran to cure various diseases. The plant is an endemic species to the country that has recently been identified in Razavi Khorasan province. To evaluate the antioxidant and anti-melanogenesis of N. binaludensis, in this study the inhibitory activity of different extracts of N. binaludensis in murine melanoma ...

Evaluation of Antioxidant and Anti-Melanogenic Activity of Different Extracts of Aerial Parts of N. Sintenisii in Murine Melanoma B16F10 Cells

Nepeta (Lamiaceae) is an important genus with beneficial medicinal properties. N. sintenisiiBornm. has been used in folk medicine of Iran to cure various diseases. We investigated theanti-melanogenesis effects of n-hexane, MeOH, CH2Cl2, n-BuOH, EtOAc, and H2O extractsisolated from the plant in B16 melanoma cells. Various assays including cytotoxicity, mushroomtyrosinase inhibition, inhibition o...